Monday, April 2, 2007

British team grows human heart valve from adult bone marrow stem cells -- Grow your own replacement organs! No rejections!

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Just when will those who are experimenting on embryonic stem cells going to realize that they are working on the wrong railroad?

A British research team led by the world's leading heart surgeon has grown part of a human heart from stem cells for the first time. If animal trials scheduled for later this year prove successful, replacement tissue could be used in transplants for the hundreds of thousands of people suffering from heart disease within three years.

Sir Magdi Yacoub, a professor of cardiac surgery at Imperial College London, has worked on ways to tackle the shortage of donated hearts for transplant for more than a decade. His team at the heart science centre at Harefield hospital have grown tissue that works in the same way as the valves in human hearts, a significant step towards the goal of growing whole replacement hearts from stem cells.
[....snip]
By using chemical and physical nudges, the scientists first coaxed stem cells extracted from bone marrow to grow into heart valve cells. By placing these cells into scaffolds made of collagen, Dr Chester and his colleague Patricia Taylor then grew small 3cm-wide discs of heart valve tissue. Later this year, that tissue will be implanted into animals - probably sheep or pigs - and monitored to see how well it works as part of a circulatory system.

If that trial works well, Prof Yacoub is optimistic that the replacement heart tissue, which can be grown into the shape of a human heart valve using specially-designed collagen scaffolds, could be used in patients within three to five years.

Growing a suitably-sized piece of tissue from a patient's own stem cells would take around a month but he said that most people would not need such individualised treatment. A store of ready-grown tissue made from a wide variety of stem cells could provide good matches for the majority of the population. [....Snip] The Guardian -- The Telegraph

It is interesting that the news about this revolutionary method of growing human tissue from other than embryonic stem cells appeared in the tenth paragraph of this fifteen paragraph story.

I think the score is now Adult Stem Cells 83, Embryonic Stem Cells, Zip!


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